ImmunoGenic 2000 Theraputic Immune Modulation

Veterinary Applications & Case Studies

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Equine Squamous Cell Carcinoma

Tango, a mixed breed white 9 year old stallion was a Rescue horse and was diagnosed with metastasized Squamous Cell Carcinoma, SCC, by Dr. James Johns of the Veterinary Medical Teaching Hospital at the University of Florida.

Tango suffered from multiple medical conditions including Strangles (Streptococcus equi bacterium), and Esophageal Varices which are abnormal, enlarged veins in the lower part of the esophagus. The Strangles was causing heavy nasal discharge of yellow and green thick purulent discharge with a very foul odor and swollen or enlarged lymph nodes in the neck. Tango’s cancerous facial lesion was bleeding and it too presented with thick pus, mostly green in color, and with a very foul odor.

SCC is a cancer of the epidermis and is a major form of skin cancer with SCC being the second most common type of tumor occurring in horses, especially in white horses. Areas of the horse most affected by SCC are 1) skin, 2) genitals, 3) lining of the stomach and intestines, 4) and the eyes. In horses, approximately 50% of SCC cases involve the eyes. SCC is caused by exposure to ultraviolet sunlight, a compromised immune system, genetics, and is thought to have a viral component. Once SCC becomes metastasized there is involvement of the lymph nodes which aids the SCC in spreading throughout the animal’s body.

Squamous cell carcinoma was diagnosed at these locations on Tango’s body:

  1. Left side of face – between commissure of mouth and nostril & approximately 8cm in diameter.
  2. Right side of upper lip approximately 1 ½ cm diameter.
  3. Two lesions (1-2 mm each) on left lower eyelid.

Surgical debridement of large left sided lesion was performed by a veterinarian at the E.T.C. Horse rescue in Ocala Florida.

Immuno-Genic Corporation, under the direction of Mary Brown, was donating Ig2000 treatments to the rescue horses and was asked to provide Ig2000 treatments for Tango.

Tango received twenty-three (23) Ig2000 treatments over an eighty-five (85) day period. Tango received an antibiotic for his Strangles infection but was not receiving any other medications. Upon receiving Ig2000 treatments, Tango exhibited signs of feeling better, i.e. increased appetite, playful, more energy, less pain. The SCC showed signs of regression as the following pictorials will demonstrate. The Ig2000 treatments kept the SCC from further invading the jaw and nasal area and provided Tango with an “Improved Quality of Life”.

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